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Viruses
- African horse sickness virus
- African swine fever virus
- Akabane virus
- Avian influenza virus (highly pathogenic)
- Blue tongue virus (exotic)
- Camel pox virus
- Cercopithicine Herpes I virus (Herpes B virus)
- Classical swine fever virus
- Crimean-Congo hemorrhagic fever virus
- Eastern equine encephalitis virus
- Ebola viruses
- Foot and mouth disease virus
- Goat pox virus
- Japanese encephalitis virus
- Lassa fever virus
- Lumpy skin disease virus
- Malignant catarrhal fever
- Marburg virus
- Menangle virus
- Monkey pox virus
- Newcastle disease virus (velogenic)
- Nipah and Hendra complex virus
- Peste des petits ruminants
- Rift Valley fever virus
- Sheep pox virus
- South American hemorrhagic fever viruses (Junin, Machupo, Sabia, Flexal, Guanarito)
- Swine vesicular disease virus
- Tick-borne encephalitis complex (flavi) viruses (Central European, Far Eastern [Russian Spring and Summer encephalitis, Kyasanur Forest disease, Omsk Hemorrhagic Fever])
- Variola major (Smallpox), Variola minor (Alastrim)
- Venezuelan equine encephalitis virus
- Vesicular stomatitis virus (exotic)
Prions
- Bovine spongiform encephalopathy agent
Bacteria
- Bacillus anthracis
- Botulinum neurotoxin producing strains of Clostridium
- Brucella abortus, B. suis and B. melitensis
- Burkholderia mallei and B .pseudomallei
- Cowdria ruminatum (Heartwater)
- Coxiella burnetii
- Francisella tularensis
- Liberobacter africanus
- Liberobacter asiaticus
- Mycoplasma capriolu/M. F38/ M. capri
- Mycoplasma mycoides mycoides
- Ralstonia solanacearum race 3, biovar 2
- Rickettsia prowazekii and R. rickettsii
- Xanthomonas oryzae pv. Oryzicola
- Xyella fastidiosa (citrus variegated chlorosis strain)
- Yersinia pestis
Fungi
- Coccidioides immitis and C. posadasii
- Peronosclerospora philippinensis
- Sclerophthora rayssiae var zeae
- Synchtrium endobioticum
Genetic elements, recombinant Nucleic Acids, and Recombinant Organisms
- Nucleic acids that can produce infectious forms of any of the select agent viruses.
- Recombinant nucleic acids that encode for the functional form(s) of any of the select agent toxins if the nucleic acids: a) can be expressed in vivo or in vitro; or b) are in a vector or recombinant host genome and can be expressed in vivo or in vitro.
Toxins and their regulated quantities
- Abrin > 100 mg
- Botulinum neurotoxins > 0.5mg
- Clostridium perfringens epsilon toxin > 100 mg
- Conotoxins > 100 mg
- Diacetoxyscirpenol > 1,000 mg
- Ricin > 100 mg
- Saxitoxin > 100 mg
- Shigatoxin > 100 mg
- Shiga-like ribosome inactivating proteins > 100 mg
- Staphylococcal enterotoxins > 5 mg
- Tetrodotoxin > 100 mg
- T-2 toxin > 1,000 mg
Exemptions
- Toxins in quantities below those in the listings, under the control a principal investigator, treating physician or veterinarian.
- Non-viable organisms or non-functional toxins.
- Any organism or toxin in its naturally occurring environment provided it has not been intentionally cultivated, introduced, collected or otherwise extracted from its natural source.
- Specific strains of bacteria, viruses, and fungi that pose a reduced to human, animal, or plant health in relation to the parental organism. For a complete listing, go to: http://www.aphis.usda.gov/programs/ag_selectagent/notification_of_exclusion.pdf
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